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Department of Public Health and Primary Care (PHPC)

 

Technological advances have continued to drive the study of biology towards the statistical and computational sciences. We are now able to differentiate and quantify biomolecules at levels previously unimaginable, allowing us to study their interactions and relationships to health and disease in an unbiased, systems-level manner.

The Inouye Lab aims to alleviate the burden of disease using its interdisciplinary strengths in the statistical, computational and biological sciences to leverage the latest genomic and multi-modal technologies.

We focus on research questions in cardiovascular and respiratory disease but maintain broad interests, including:

We operate in an extremely fast-moving research environment. For a better snapshot of the current depth and breadth of projects, please see our publications and preprints. https://www.inouyelab.org/home/publications

Read more at: Methodology Development and Translational Research

Methodology Development and Translational Research

There are two themes of research: Methodology development: I am interested in developing statistical methods to understand the molecular architecture (DNA, RNA, proteomics, metabolomics) of health outcomes (disease, treatment responses, comorbidity). In statistical terminology, I work on dimension...


Read more at: Environmentally sustainable computational science
Tree growing on the converging point of computer circuit board

Environmentally sustainable computational science

Computing is an essential component of modern science, and it comes with significant, but not always well-understood, environmental impacts. E.g. the global carbon footprint of data centres is estimated to be equivalent to the entire US commercial aviation, and individual scientific projects...


Read more at: Genetic Prediction of Multi-omics
DNA strands

Genetic Prediction of Multi-omics

Recent advancements in high-throughput multi-omics technologies have enabled simultaneous measurement of many thousands of biomolecules across multiple biological layers (e.g. transcriptomics, proteomics and metabolomics) within the same sample. They open unprecedented opportunities to deepen our...