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Department of Public Health and Primary Care (PHPC)

 

Biography

Siyuan grew up in Shanghai, China, and completed his BSc in Biological Sciences at Fudan University in 2020, where he developed an interest in genomics and bioinformatics. After graduation, he joined the Computational Biology and Quantitative Genetics program at the Harvard School of Public Health. Siyuan completed his Master’s thesis in Prof. Isaac Kohane’s lab, focusing on genetic analysis among cancer exceptional responders. He reported that polygenic risk scores for autoimmune diseases are significantly different in cancer exceptional responders compared to typical cancer patients. He then worked as a computational biology research associate at the Shanghai AI Laboratory for around two years, gaining experience in several scRNA projects before becoming a PhD student at Inouye Lab. His current research aims to develop a methodological framework to link cellular characteristics from scRNA datasets to GWAS results.

Research

Single cell Statistical genetics

Publications

Chen, S., Tan, A.L.M., Saad Menezes, M.C. et al. Polygenic risk scores for autoimmune related diseases are significantly different in cancer exceptional responders. npj Precis. Onc. 8, 120 (2024). https://doi.org/10.1038/s41698-024-00613-x

PhD Research Student

Contact Details

sc2514@cam.ac.uk

Affiliations