Biography
Since October 2008, Jonathan Mant has been Professor of Primary Care Research at the University of Cambridge. He was Head of the Primary Care Unit within the University Department of Public Health & Primary Care for 8 years (2013-2021). He was appointed an NIHR Senior Investigator in April 2015 and an Emeritus NIHR Senior Investigator in 2023. He is an honorary consultant in Public Health for the Office for Health Improvement and Disparities (OHID), Department of Health & Social Care, and a Fellow of the Academy of Medical Sciences (appointed 2018). His research has focussed on evaluations of interventions and diagnostic tests in cardiovascular disease (particularly atrial fibrillation; stroke, hypertension and heart failure) in primary care. He currently leads leads the Screening with Atrial FIbrillation with ECG to Reduce stroke (SAFER) programme, and co-leads the Primary Breathe programme with Anna Spathis, and the post-stroke COMBAT fatigue programme with Grace Turner (Birmingham).
Publications
Sheppard JP , et al. Effect of antihypertensive deprescribing on hospitalisation and mortality: long-term follow-up of the OPTiMISE randomised controlled trial. Lancet Healthy Longev 2024; 5(8) e567-e573
Mant J, et al. Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial. BMJ Open 2024;14:e082047. doi: 10.1136/bmjopen-2023-082047
Hibbitt K et al. Reliability of single-lead electrocardiogram interpretation to detect atrial fibrillation: insights from the SAFER feasibility study. Europace 2024; 26 (7), euae181
Mant J, et al. The feasibility of population screening for paroxysmal AF using hand held ECG devices. EP Europace 2024; 26 (3), euae056.
Mullis R, et al. Developing primary care services for stroke survivors: the Improving Primary Care After Stroke (IPCAS) research programme. Southampton (UK): National Institute for Health and Care Research; 2024 Feb. (Programme Grants for Applied Research, No. 12.01.) Available from: https://www.ncbi.nlm.nih.gov/books/NBK601028/ doi: 10.3310/AYHW3622
Mendonça SC, et al. Progression of stroke risk in patients aged <65 years diagnosed with atrial fibrillation: a cohort study in general practice. British Journal of General Practice 2023;73:e825-31.
Yang Z et al. Association of major blood lipids with post‐stroke dementia: A community‐based cohort study. European Journal of Neurology 2022; 29 (4), 968-979
Yang Z, et al. Statin use is associated with lower risk of dementia in stroke patients: a community-based cohort study with inverse probability weighted marginal structural model analysis. European Journal of Epidemiology, 2022; 1-13
Sheppard JP et al. Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients with Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial. JAMA. 2020 May 26; 323(20): 2039-2051
Lowres N, et al. Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals. PLoS Med. 2019 Sep 25;16(9):e1002903
