Biography
Angela received her BSc (Hons) in Mathematics and Statistics in 1998 and subsequently completed her doctorate with Profs Peter Diggle and Robin Henderson from the University of Lancaster in 2001. She carried out post-doctoral research with Prof Ian White at the MRC Biostatistics Unit, Cambridge and was appointed in 2006 to University Lecturer in Biostatistics in the Department of Public Health and Primary Care, Cambridge. She now holds the position as Professor of Biostatistics and Health Data Science in the Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Cambridge. Angela holds leadership roles for major national and local health data science initiatives, including co-Lead of the Big Data for Complex Disease Driver Programme for HDR UK; BHF Data Science Centre Associate Director and Theme Lead for Structured Data; co-Lead of the NIHR Cambridge BRC Data Science and Population Health theme; Regional co-Lead for Health Data Research UK Cambridge; Programme Leader in the NIHR Blood and Transplant Research Unit in Donor Health and Behaviour; Turing Fellow at the Alan Turing Institute and a Steering Group Member of the European Society of Cardiology Cardiovascular Risk Collaboration Unit. Angela is Vice-Master of Darwin College, and College Tutor.
Research
Angela's research focuses on the frontiers of big data and epidemiology, underpinned by major population resources and informed by applied questions of major population health and global importance. She has developed novel methods and applied them in the analysis of large, complex datasets (e.g., ~67M individuals in CVD-COVID-UK consortium; >3M participants in Emerging Risk Factors Collaboration, EPIC-CVD and UK Biobank), providing new insights into chronic diseases, mainly cardiovascular and cancer. With the BHF Data Science Centre and in partnership with NHS Digital, she has helped to establish access to the England-wide Electronic Health Record resource on >55M people and is developing innovative and principled methods for reproducible analysis of the resource. In biostatistics methodology research, she focuses largely on methods for utilising electronic health records to produce unbiased results for medical/epidemiological research, including handling measurement error, using repeated measures of risk factors, missing data problems, multiple imputation, risk prediction and meta-analysis.
Publications
See google scholar: https://scholar.google.co.uk/citations?user=urLZUHwAAAAJ&hl=en
1. Robert A Fletcher, Patrick Rockenschaub, Brendon L Neuen, Isabel Johanna Walter, Nathalie Conrad, Mehrdad A Mizani, Thomas Bolton, Claire A Lawson, Christopher Tomlinson, Stelios Boulitsakis Logothetis, Carmen Petitjean, Luigi Filippo Brizzi, Stephen Kaptoge, Elena Raffetti, Patrick A Calvert, Emanuele Di Angelantonio, Amitava Banerjee, Mamas A Mamas, Iain Squire, Spiros Denaxas, Theresa A McDonagh, Cathie Sudlow, Steffen E Petersen, Glenn M Chertow, Kamlesh Khunti, Johan Sundström, Clare Arnott, John G F Cleland, John Danesh, John J V McMurray, Muthiah Vaduganathan, Angela M Wood. Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. The Lancet Public Health 2024;9:e871–e885.
2. Adam Timmis, Victor Aboyans, Panos Vardas, Nick Townsend, Aleksandra Torbica, Maryam Kavousi, Giuseppe Boriani, Radu Huculeci, Denis Kazakiewicz, Daniel Scherr, Efstratios Karagiannidis, Marta Cvijic, Agnieszka Kapłon-Cieślicka, Barbara Ignatiuk, Pekka Raatikainen, Delphine De Smedt, Angela Wood, Dariusz Dudek, Eric Van Belle, Franz Weidinger, ESC National Cardiac Societies , European Society of Cardiology: the 2023 Atlas of Cardiovascular Disease Statistics, European Heart Journal, 2024; 45; 4019–4062.
3. Elena Raffetti, Thomas Bolton, John Nolan, Luisa Zuccolo, Rachel Denholm, Gordon Smith, Ashley Akbari, Katie Harron, Gwenetta Curry, Elias Allara, Deborah A Lawlor, Massimo Caputo, Hoda Abbasizanjani, Tim Chico, Angela M Wood. COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy outcomes of 865,654 women in England and Wales: a population-based cohort study. The Lancet Regional Health–Europe, 2024: 45.
4. Zhe Xu, Juliet Usher-Smith, Lisa Pennells, Ryan Chung, Matthew Arnold, Lois Kim, Stephen Kaptoge, Matthew Sperrin, Emanuele Di Angelantonio, Angela M Wood. Age and sex specific thresholds for risk stratification of cardiovascular disease and clinical decision making: prospective open cohort study. BMJ Medicine 2024.
5. Steven Kerr, Stuart Bedston, Genevieve Cezard, Alexia Sampri, Siobhan Murphy, Declan T Bradley, Kirsty Morrison, Ashley Akbari, William Whiteley, Christopher Sullivan, Lynsey Patterson, Kamlesh Khunti, Spiros Denaxas, Thomas Bolton, Samaira Khan, Alan Keys, David Weatherill, Karen Mooney, Jan Davies, Lewis Ritchie, Jim McMenamin, Frank Kee, Angela Wood, Ronan A Lyons, Cathie Sudlow, Chris Robertson, Aziz Sheikh. Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales. The Lancet 2024; 403;554-566.
Teaching and Supervisions
Angela leads the Advanced Biostatistics in Epidemiology Module in the MPhil in Population Health Sciences, University of Cambridge
