CLINICAL RESEARCH ASSOCIATE
BSc. MB BChir
Garth works in the Cambridge Primary Care Cancer Group and is currently undertaking a Cancer Research UK funded PhD as part of the CanTest program (https://www.cantest.org). He graduated from the University of Cambridge in 2012 and went on to undertake an Academic Foundation Training post followed by an NIHR Academic Clinical Fellowship in General Practice in Manchester. While Garth’s current research focusses on primary care cancer detection, he also has experience in lab based cancer research, having worked in cancer research labs in the UK, France and Singapore.
Garth is interested in the role primary care can play in the early detection of cancers and particularly in diagnostic test research. His PhD work focuses on the evaluation of tests for the detection of ovarian cancer in the primary care setting. This work principally involves the use of routinely collected data sources including the Clinical Practice Research Datalink (CPRD, primary care data) and Cancer Registry data.
Garth is Co-Principal Investigator on a Wellbeing of Women funded study, currently underway in Manchester, which seeks to determine the diagnostic performance of cancer biomarkers for ovarian cancer in the symptomatic primary care population.
Garth has been heavily involved in medical education since university and has a particular interest in engaging students in research. He is Co-Founder of the Wellcome Trust funded National Student Association of Medical Research (https://nsamr.ac.uk). Garth enjoys hands on teaching and mentoring, and supervises student attachments within the Cancer Group.
Full list available: http://www.researchgate.net/profile/Garth_Funston/research
Funston G, Hamilton W, Abel G, Crosbie EJ, Rous B, Walter FM. The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: a population-based cohort study. PLoS Med 2020; 17: e1003295
Jones OT, Ranmuthu C, Hall PN, Funston G, Walter FM (2020) Recognising skin cancer in primary care. Adv Ther. 37:603-16.
Funston G, Van Melle M, Baun ML, Jensen H, Helsper C, Emery J, Crosbie EJ, Thompson M, Hamilton W, Walter FM (2019) Variation in the initial assessment and investigation for ovarian cancer in symptomatic women: a systematic review of international guidelines. BMC Cancer. 1;19(1):1028
Zhou Y, Funston G, Lyratzopoulos G, Walter FM (2019) Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care. Adv Ther. 7:1-8
Merriel SW, Funston G, Hamilton W (2018) Prostate cancer in primary care. Adv Ther. 35(9):1285-94.
Funston G, O’Flynn H, Ryan NAJ, Hamilton W, Crosbie E (2018) Recognising gynaecological cancer in primary care: risk factors, red flags and referrals. Adv Ther. 35(4):577-589
Funston G, Piper R, Connell C, Foden P, Young A, O’Neill P (2016) Medical student perceptions of research and research-orientated careers: an international questionnaire study. Med Teach. 38(10):1041-1048
Funston G, Cerra C, Kirkham D, Doherty G, O’Neill P (2015) The road to a clinical academic career. BMJ Careers
Sanderson B, Funston G (2015) A novel international initiative to promote academic oncology to medical students. Med Teach. 37(1):98
Funston G (2015) The potential of student-led initiatives to revitalise general practice. BJGP. 65(639):531
Russell C, Young A, Lomas D, Funston G (2014) Evaluating the National Student Association of Medical Research. MedEduc. 48(11):1105-6
Funston G, Goh W, Wei SJ, Tng QS, Brown C, Tong LJ, Verma C, Lane D, Ghadessy F (2012) Binding of Translationally Controlled Tumour Protein to the N-Terminal domain of HDM2 is inhibited by Nutlin-3. PLoS ONE. 7(8):e42642
Funston G, Young AM (2012) Action is required to safeguard the future of academic medicine in the UK. Nat Med. 18(2):194
Funston G, Kallioinen SE, Felipe P, Ryan MD, Iggo RD (2008) Expression of heterologous genes in oncolytic adenoviruses using picornaviral 2A sequences that trigger ribosome skipping. J Gen Virol. 89(Pt 2):389-96
Grants and Research Awards
2018– National Institute for Health Research (NIHR Grant, Principal Investigator
Purpose: Evaluate the diagnostic performance of CA125 in primary care
2018– CanTest PhD Fellowship
Purpose: To fund PhD research into tests for the early detection of ovarian cancer in primary care
2017 – Wellbeing of Women Entry Level Scholarship
Purpose: To investigate the utility of ovarian cancer biomarkers in primary care
2011 – Singapore International Pre-Graduate Award
Purpose: To fund a medical elective undertaken in Professor Sir David Lane’s Singapore lab
2011 – Wellcome Trust Grant, Co-Principal Investigator
Purpose: To fund the establishment of a National Student Association of Medical Research
2010 – Wellcome Trust Grant, Co-Principal Investigator
Purpose: To fund the establishment of the Cambridge University Clinical Research Society
2009 – Wellcome Trust Student Research Bursary
Purpose: To fund research undertaken during a summer vacation
2008 – Wolfson Intercalated Award
Purpose: To fund an intercalated research degree