Background

Tom is a mathematician who works in our data management team and as part of the National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics.

Research Interests

Tom is currently working under the stratified approaches programme at the NIHR BTRU.

Recent Publications

Moore C, Bolton T, Walker M, et al. Recruitment and representativeness of blood donors in the INTERVAL randomised trial assessing varying inter-donation intervals. Trials 2016; 17(1): 458.

Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Bolton T, et al. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. The Lancet 2018; 391(10129): 1513-23.

Burgess S, Ference BA, Staley JR, Freitag DF, Mason AM, Nielsen SF, Willeit P, Young R, Surendran P, Karthikeyan S, Bolton TR, et al. Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis. JAMA Cardiology 2018; 3(7): 619-27.

Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, Burgess S, Willeit P, Bolton T, et al. Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies. European Heart Journal 2018; 40(7): 621-31.

Schooling CM, Luo S, Au Yeung SL, Thompson DJ, Karthikeyan S, Bolton TR, et al. Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation. International Journal of Cardiology 2018; 267: 171-6.

Gregson J, Kaptoge S, Bolton T, et al. Cardiovascular Risk Factors Associated With Venous Thromboembolism. JAMA Cardiology 2019; 4(2): 163-73.

Alaa AM, Bolton T, Di Angelantonio E, Rudd JHF, van der Schaar M. Cardiovascular disease risk prediction using automated machine learning: A prospective study of 423,604 UK Biobank participants. PLOS ONE 2019; 14(5): e0213653.

Sun Y-Q, Burgess S, Staley JR, Wood AM, Bell S, Kaptoge SK,Guo Q, Bolton TR, et al. Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses. BMJ 2019; 364: l1042.

Kaptoge S, Pennells L, De Bacquer D, Cooney MT, Kavousi M, Stevens G, Riley LM, Savin S, Khan T, Altay S, Amouyel P, Assmann G, Bell S, Ben-Shlomo Y, Berkman L, Beulens JW, Björkelund C, Blaha M, Blazer DG, Bolton T, et al. World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions. The Lancet Global Health 2019; 7(10): e1332-e45.

Browne A, Fisher SA, Masconi K, Smith G, Doree C, Chung R, Rahimzadeh M, Shah A, Alonso Rodriguez S, Bolton T, et al. Donor Deferral Due to Low Hemoglobin—An Updated Systematic Review. Transfusion Medicine Reviews 2020; 34(1): 10-22.