Research Assistant in Computational Immunobiology
Marika joined PHPC in 2019, shortly after completing her PhD in Immunogenetics at King’s College London, under the supervision of Dr. Francesca Capon and Prof. Francesca Ciccarelli. Her project investigated the pathogenesis of rare immune-mediated diseases leading to the discovery of a novel mechanism linking IL-36 sustained signalling and IFN- α production.
In her postdoc position as computational immunobiologist in Inouye’s lab she will investigate the role of long-lived plasma cells in the human gut and their interaction with the gut microbiota as well as pursuing her interest in investigating the molecular mechanisms of gene expression.
Mahil SK1, Catapano M1,2, Di Meglio P1,3, Dand N1, Ahlfors H4, Carr IM5, Smith CH1, Trembath RC1, Peakman M6, Wright J7, Ciccarelli FD2,8, Barker JN1, Capon F9. An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target. Sci Transl Med. 2017 Oct 11;9(411)
Grassi E1, Mariella E1, Forneris M1,2, Marotta F1, Catapano M1,3, Molineris I4, Provero P5,6. A functional strategy to characterize expression Quantitative Trait Loci. Hum Genet. 2017 Nov;136(11-12):1477-1487