Research Associate

Email: jeam4@medschl.cam.ac.uk

 Background

Jess completed her BSc (Hons) in Sports Science/Exercise Physiology in 2007. She shortly joined the MRC Epidemiology Unit as a Research Assistant, followed by the Cambridge Clinical Trials Unit as a Clinical Trials Coordinator. She completed her PhD in the Division of Experimental Medicine and Immunotherapeutics in 2017.

Jess joined the Cardiovascular Epidemiology Unit in August, 2017.

Research Interests

Jess’s PhD focused on the physiological mechanisms underlying the association between obesity and haemodynamics, specifically adaptation of the peripheral vasculature, in young adults. She is currently working across a range of recall-by-genotype studies in healthy volunteers and in patients with thoracic aneurysms. These studies will help determine distinct molecular and cellular mechanisms underlying candidate functional variants identified in large-scale genetic studies of human traits and diseases.

Selected Publications

Middlemiss JE, Miles KL, McDonnell BJ, Yasmin, Maki-Petaja KM, Cockcroft JR, et al. 2016. Mechanisms underlying elevated SBP differ with adiposity in young adults: the Enigma study. Journal of Hypertension. 34:290-7.

Middlemiss JE, McEniery C. 2017. Feeling the pressure: (patho) physiological
mechanisms of weight gain and weight loss in humans. Hypertension Research. 40:226-36.

Additional Information

Jess is a part-time personal trainer since completing her undergraduate degree, and has always been a heavy promoter of exercise and a healthy balanced diet as a lifestyle/preventive intervention for weight control and associated metabolic disorders.