Research Associate

Email:  ev250@medschl.cam.ac.uk

Background

Elena obtained a PhD in Immunology at the University of Barcelona, Spain, and worked for several years on gene regulation on the immune system. In 2015 she completed a MPhil in Epidemiology at Cambridge University.

Research Interests

Elena joined the Cardiovascular Epidemiology Unit in September 2015 to investigate inflammatory pathways that are causally implicated in cardiovascular disease.

Selected Publications

Vigorito E, Kuchenbaecker KB, Beesley J, […],Chenevix-Trench G, Antoniou AC. Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. PLoS One. 2016 Jul 27;11(7):e0158801.

 

Nakagawa R, Leyland R, Meyer-Hermann M, Lu D, Turner M, Arbore G, Phan TG, Brink R, Vigorito E. MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis. J Clin Invest. 2016 Jan;126(1):377-88.

 

Lu D, Nakagawa R, Lazzaro S, Staudacher P, Abreu-Goodger C, Henley T, Boiani S, Leyland R, Galloway A, Andrews S, Butcher G, Nutt SL, Turner M, Vigorito E. The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B celldifferentiation. J Exp Med. 2014 Oct 20;211(11):2183-98.

 

Turner M, Galloway A, Vigorito E. Noncoding RNA and its associated proteins as regulatory elements of the immune system. Nat Immunol. 2014 Jun;15(6):484-91.