New evidence on the impact of the COVID-19 pandemic on GP assessment of patients who may have cancer indicates need for urgent action. The COVID-19 pandemic has dramatically influenced different aspects of patients’ cancer pathways, from diagnosis to treatment, mortality and survival. Implications are also likely early in the diagnostic pathway, from symptom presentation to […]
Research Alert: Improving screening for bowel cancer using risk stratification
Age is the most important risk factor for bowel cancer but many genetic and lifestyle risk factors have been identified. There is interest in whether information about these factors could be used to improve screening programmes for bowel cancer. See this article as a shareable feature In research funded by Bowel Cancer UK and led […]
Artificial intelligence techniques could help with earlier diagnosis of cancer in primary care: a systematic review
Artificial Intelligence (AI) techniques can be applied to primary care data to facilitate the early diagnosis of cancer, according to the first international review of studies on this topic. Promising studies applied AI techniques to some elements of the electronic health record (EHR), but did not incorporate all of the available data. Some commercially developed […]
Biomarkers for the early detection of upper-gastrointestinal cancers in primary care: a systematic review
A new systematic review guided by the CanTest Framework found that while there is a large number of biomarkers being developed for the detection of upper GI cancers, more evidence from evaluations in low-prevalence populations like primary care is still needed before their adoption in clinical practice can be recommended. Cancers of the stomach, oesophagus, […]
The BEST3 trial: is the Cytosponge TFF3 biomarker test oven-ready for primary care?
The Cytosponge test could help diagnosis of Barrett’s oesophagus in people who are on medication for long term heartburn. A clinical trial led by Prof Rebecca Fitzgerald in Cambridge was published on 1st August 2020 in The Lancet. Here, CanTest Chair Prof Greg Rubin, who contributed primary care expertise to the trial, explains more about the test and […]
Imaging activity possibly signalling missed diagnostic opportunities in bladder and kidney cancer: a longitudinal data-linkage study using primary care electronic health records
Blog by Dr Yin Zhou, Clinical Research Fellow, Cancer Group Patterns of events before the diagnosis of cancer may reveal ‘signals’ for missed diagnostic opportunities for patients. Earlier research, including from our CanTest collaborators in Denmark, has shown that increase in background rate of consultations, prescriptions and laboratory test use occur long before cancer diagnosis. […]
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