|Title:||Biomarkers for the early detection of gastro-intestinal cancers in primary care|
|Project Description:||Gastrointestinal (GI) symptoms are common in the community. It is important that general practitioners can tell apart serious conditions such as cancer from less serious conditions like irritable bowel syndrome. However, this is difficult because symptoms of cancer can be very non-specific. As a result, many patients are referred for endoscopy (an invasive procedure), and most of them will be found not to have cancer.
Lots of research is being done looking at biomarkers (markers that can be detected in a blood or urine for example and can be used to differentiate between the presence or absence of disease such as cancer), but most of this research is being done in specialist settings. We are carrying out a systematic review to identify biomarkers that have the potential to be used in primary care to help with the early detection of GI cancers.
|Start date:||1st October 2019|
|End date:||30th September 2020|
|Contact person:||Dr Natalia Calanzani|
|Contact Details:||Telephone: +44 (0)1223 748694
|Further Information, References and Publications|
Druce P, Calanzani N, Snudden C, et al. Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Lower Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. Adv Ther, 2021. https://doi.org/10.1007/s12325-021-01645-6
For more information visit https://www.phpc.cam.ac.uk/pcu/research/research-groups/cancer-group/early-detection-and-diagnosis/