Title: | CoMMiSS – Clustering of multi-morbidity in stroke survivors |
Project Description: | Multimorbidity accounts for 25% of the adult UK population, and over half of hospital admissions and GP appointments. Multimorbidity is particularly prevalent in stroke/transient ischaemic attack (TIA) survivors (~94%). Despite the high prevalence of multimorbidity in stroke/TIA patients, no studies have investigated how multimorbidity is structured within the stroke/TIA survivor population. |
Methodology description: | Using the Clinical Practice Research Datalink (CPRD) GOLD database, which provides clinical primary care data from UK general practices, this research aims:
In a cross-sectional approach, we focus on adults surviving a stroke/ TIA. Utilizing a 3-year follow up period we estimate death, primary care consultation and hospital admission rates. We link the CPRD GOLD data with area socioeconomic deprivation data and Hospital Episodes Statistics. Multimorbidity is defined as having two or more of 36 long-term conditions. A model-based person-centred cluster analysis, the latent class analysis (LCA) calculating the class membership probabilities among patients is used. The number of clusters is defined through statistical criteria and clinical input. We describe the clusters in terms of comorbidities and identify key characteristics and health outcomes associated with them. |
Project organisation | |
Start date: | 1st November 2020 |
End date: | 31st March 2021 |
Contact person: | Dr Lina Massou |
Contact Details: | Primary Care Unit Institute of Public Health Research Forvie Site Robinson Way Cambridge CB2 0SR E-mail: em716@medschl.cam.ac.uk |
Funding information | |
Funding Organisation: | National School of Primary Care Research |
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Further Information, References and Publications | |