The Clinical Practice Research Datalink (CPRD) is an anonymised database of the primary care records of five million current UK patients. It is linked to an increasing range of other clinical “big data” such as Hospital Episode Statistics (HES), death certification records, and disease registries in areas such as cancer and heart disease. Over 1,500 articles have been published using CPRD, and the number increases every year. The database not only supports the design of large observational studies, but can also support interventional studies.
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