Screen-RCC - Evaluation of potential screening strategies for kidney cancer - Primary Care Unit

Title:	Screen-RCC – Evaluation of potential screening strategies for kidney cancer
Project Description:	The overall aim of this work was to explore the potential for introducing a risk stratified kidney cancer screening programme. We will achieve this through four linked studies: 1. A review of the current evidence for kidney cancer screening 2. A systematic review to identify risk models that predict the future incidence of kidney cancer and could potentially be used to select individuals for screening 3. External validation of the risk models identified in the systematic review in the UK Biobank cohort 4. An online survey to assess population attitudes to and concerns about kidney cancer screening incorporating different tests and potential risk stratification approaches
Funder information:	Kidney Cancer UK – £35,000
Other Collaborators:	Professor Grant Stewart (Department of Surgery) Professor Simon Griffin (Primary Care Unit) Dr Hannah Harrison (Primary Care Unit) Miss Sabrina Rossi (Department of Oncology)
Project organisation
Start date:	1st October 2019
End date:	31st December 2020
Contact person:	Dr Juliet Usher-Smith
Contact Details:	Email: jau20@medschl.cam.ac.uk
Further Information, References and Publications
Publications Usher-Smith JA, Simmons R, Rossi S, Stewart GD. Current evidence on screening for renal cancer. Nature Reviews Urology. 2020 Nov;17(11):637-642. doi: 10.1038/s41585-020-0363-3. Harrison H, Thompson RE, Lin Z, Rossi S, Stewart GD, Griffin SJ, Usher-Smith JA. Risk prediction models for kidney cancer: a systematic review. European Urology Focus. 2020 Jul 14:S2405-4569(20)30190-5. doi: 10.1016/j.euf.2020.06.024. Harvey-Kelly L, Mills K, Harrison H, Rossi S, Griffin SJ, Stewart GD, Usher-Smith JA. Public attitudes towards screening for kidney cancer: an online survey. BMC Urology 2020 Oct 28;20(1):170. doi: 10.1186/s12894-020-00724-0 Usher-Smith JA, Harvey-Kelly L, Harrison H, Rossi S, Griffin SJ, Stewart GD. Acceptability and potential impact on uptake of using different risk stratification approaches to determine eligibility for screening: A population-based survey. Health Expectations. 2020 Dec 2. doi: 10.1111/hex.13175.