Title: | Does adding facilitated behaviour change improve outcomes for people with diabetes detected by screening? The ADDITION Plus study |
Principal research question: | What is the effect on modeled cardiovascular risk and the cost (economic and psychological) of a behavioural intervention for people aged 40 to 69 years with screen-detected diabetes?
Can an approach, based on theory and evidence from psychology, to increase and maintain health-promoting behaviours (physical activity, taking medication and dietary change) achieve clinically important and measurable change in these behaviours when offered to people with screen-detected diabetes? What are the added benefits and costs of facilitation of healthy behaviours among people aged 40 to 69 years with diabetes detected by screening and intensively treated? |
Methodology description: | Practices were randomised to screening for diabetes followed by routine care according to national guidelines (RC) or screening followed by intensive multifactorial intervention (IT). This included prescription of an angiotensin converting enzyme inhibitor (ACE) and aspirin, followed by stepwise target-led treatment to reduce hyperglycaemia, blood pressure, hyperlipidaemia and microalbuminuria. Within the intensive treatment arm, physical activity, medication adherence and diet were also assessed. |
Sample group description: | 40-69 year olds in Eastern region, who are at high risk of prevalent undiagnosed diabetes, in selected practices which were representative of the national population. |
Outcome measure description: | The results (currently in analysis) will be of immediate relevance to policy decisions about screening for diabetes, and subsequent management of screen-detected cases, nationally and internationally. They will inform approaches to health promotion, to the management of chronic disease and risk, and to strategies to promote physical activity and support medication adherence. They will be generalisable to conditions other than diabetes and settings other than primary care, and have implications for training of practitioners, and involvement of patients. |
Project organisation | |
Start date: | 1st June 2001 |
End date: | 1st November 2006 |
Contact person: | Dr Kate Williams |
Contact Details: | Primary Care Research Unit Institute of Public Health University Forvie Site, Robinson Way Cambridge Cambs CB2 0SR UK Telephone: (01223) 330332 Fax: 01223 762515 E-mail: kmw36@medschl.cam.ac.uk |
Funding information | |
Funding Organisation: | Medical Research Council |
Funding Reference: | MRC G0001164 |
Funding Amount: | £543,614 |
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Funding Organisation: | NHS R&D Support Funding |
Funding Reference: | 2005/06 |
Funding Amount: | £183,387 |
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References and Publications | |