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Read more at: Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease

Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease

8 May 2025

Carles Foguet and Michael Inouye, Cardiovascular Epidemiology Unit Department of Public Health and Primary Care A major challenge in understanding the contribution of genetic variation to disease risk is the fact that genetic variants can act within complex biological networks, such as the human metabolic network, which...

Read more at: Proteogenomic signatures of type 2 diabetes and its comorbidities

Proteogenomic signatures of type 2 diabetes and its comorbidities

8 May 2025

Dirk S Paul and Michael Inouye, Cardiovascular Epidemiology Unit Department of Public Health and Primary Care We are delighted to share our work on the proteogenomics of type 2 diabetes and related comorbidities published in Nature Communications . The study used large-scale genomic and proteomic data from the UK Biobank...

Read more at: How do GPs’ new ways of working affect community nurses? A qualitative study

How do GPs’ new ways of working affect community nurses? A qualitative study

8 May 2025

Research led by Dr Ben Bowers and Dr Louisa Polak, PELiCam (pictured above), have explored how reshaping collaboration between GPs and community nurses is having mixed implications for palliative care. The study,  published in the British Journal of General Practice , found community nurses described how they are...

Read more at: Removing ovaries and fallopian tubes linked to lower risk of early death among certain breast cancer patients

Removing ovaries and fallopian tubes linked to lower risk of early death among certain breast cancer patients

8 May 2025

Women diagnosed with breast cancer who carry particular BRCA1 and BRCA2 genetic variants are offered surgery to remove the ovaries and fallopian tubes as this dramatically reduces their risk of ovarian cancer. Now, Cambridge researchers have shown that this procedure – known as bilateral salpingo-oophorectomy (BSO) – is...

Read more at: University of Cambridge study becomes the largest randomised atrial fibrillation screening trial ever undertaken

University of Cambridge study becomes the largest randomised atrial fibrillation screening trial ever undertaken

15 April 2025

Over 89,000 participants are taking part in the largest ever randomised clinical trial of screening to detect atrial fibrillation (AF). The SAFER trial, funded by the National Institute for Health and Care Research (NIHR), is working with 197 GP practices across England to determine whether systematic AF screening can...

Read more at: Introducing Our Four New ARC Early-Career Clinical Academic Nurse Fellows 

Introducing Our Four New ARC Early-Career Clinical Academic Nurse Fellows 

9 April 2025

The Primary Care Unit (PCU) is delighted to welcome four new ARC Fellows, all early-career Clinical Academic Nurses, who will be leading impactful research projects to advance palliative and community care. Their fellowships, supported by Dr Ben Bowers and Dr Simon Etkind, highlight the growing strength of clinical...

Read more at: How do GPs’ new ways of working affect community nurses? A qualitative study

How do GPs’ new ways of working affect community nurses? A qualitative study

28 March 2025

Researchers from the University of Cambridge have found that community nurses providing palliative care find collaborating with GPs harder, where practices have moved towards remote communication and workforce diversification. The study, published in the British Journal of General Practice , explores how reshaping...

Read more at: New resource launched to share the evidence base for anticipatory prescribing in end of life care

New resource launched to share the evidence base for anticipatory prescribing in end of life care

15 January 2025

The anticipatory prescribing of injectable medications is a common practice to manage symptoms for people receiving end-of-life care at home or in care homes. Despite its widespread use, there is limited evidence into acceptability, safety and clinical effectiveness of anticipatory prescribing. In this resource for...

Read more at: Public perception of the physician associate profession in the UK: a systematic review
Image of Dr Shobhana Nagraj

Public perception of the physician associate profession in the UK: a systematic review

7 January 2025

Dr Shobhana Nagraj co-led a recent article in BMC Health Services Research examining public perceptions of the physician associate (PA) role in the UK. Amid ongoing scrutiny of PAs’ responsibilities and prescribing rights, the study reviewed 15 studies and highlighted significant public confusion about the role, with many...

Read more at: Launch of the East London NHS Foundation Trust - University of Cambridge Implementation Research Hub
The East London NHS Foundation Trust (ELFT) - University of Cambridge Implementation research Hub

Launch of the East London NHS Foundation Trust - University of Cambridge Implementation Research Hub

7 January 2025

On September 27th 2024, the group launched the East London NHS Foundation Trust (ELFT) - University of Cambridge Implementation research Hub in Luton, Bedfordshire. The Hub, led by Dr Shobhana Nagraj working in partnership with ELFT, aims to increase research capacity in Luton & Bedfordshire, and, through reciprocal...

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