Selected Publications

2008

Bennet A, Di Angelantonio E, Erquo S, Eiriksdottir G, Sigurdsson G, Wooward M, Rumley A, Lowe GDO, Danesh J, Gudnason V. Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data.  Arch Int Med 2008; 168 (6): 598–608

Danesh J, Kaptoge S, Mann A, Sarwar N, Wood A, Angleman S, Wensley F, Higgins J, Lennon L, Eiriksdottir G, Rmley A, Whincup P, Lowe G, Gudnason V. Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review.  PLoS Medicine 2008;5 (4): e78

Thompson A, Di Angelantonio E, Sarwar N, Erquo S, Salaheen D, Dullaart R, Keavney B, Ye Z, Danesh J. Association of Cholesteryl Ester Transfer Protein Genotypes with CEPT Mass and Activity, Lipid Levels and Coronary Risk.  JAMA 2008; 299 (23): 2777–2788

Casas JP, Shah T, Hingorani AD, Danesh J, Pepys MB. C-reactive protein and coronary heart disease: a critical review.  J Int Med; 264; 295–314

Sagoo GS, Tatt I, Salanti G, Butterworth AS, Sarwar N, van Maarle M, Jukema JW, Wiman B, Kastelein JPJ, Bennet A, de Faire U, Danesh J, Higgins JPT. Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis.  Am J Epidemiol 2008 [Epub ahead of print]

2007

Easton D, Dunning AM, Cox A, Pharoah P. A common coding variant in CASP8 is associated with breast cancer risk.  Nature Genetics 2007; 39 (3): 352–8

Sandu M, Barroso I, Wareham N, Pharoah P. Common variants in WFS1 confer risk of type 2 diabetes.  Nature Genetics 2007; 39 (8): 951–953

Sarwar N, Danesh J, Eiriksdottir G, Sigurdsson G, Wareham N, Bingham S, Boekholdt SM, Khaw KT, Gudnason V. Triglycerides and the risk of coronary heart disease: 10158 incident cases among 262525 participants in 29 western prospective studies.  Circulation 2007, Jan 30, 115(4) 450–458

Di Angelantonio E, Danesh J, Eiriksdottir G, Gudnason V. Renal function and risk of coronary heart disease in general populations: new perspective study and systematic review.  PLoS Medicine 2007 4 (9) 1497–1507

Bennet A, Di Angelantonio E, Ye Z, Wensley F, Dhalin A, Ahlborn A, Keavney B, Collins R, Wiman B, de Faire U, Danesh J. Associations of apolipoprotein E genotypes with lipid levels and coronary risk.  JAMA 2007; 298 (11): 1300–1311

Sarwar N, Sattar N, Gudnason V, Danesh J. Circulating concentrations of insulin markers and coronary heart disease: a quantitative review of 19 Western prospective studies.  Eur Heart J 2007; 28 (20): 2491–2497

Higgins J, Little J, Ioannidis J, Teri M, Smeeth L, Sterne J, Anagnostelis B, Butterworth A, Danesh J, Dezateux C, Gallacher J, Gwinn M, Lewis S, Minelli C, Pharoah P, Slaanit G, Sanderson S, Smith L, Taioli E, Thompson J, Thompson S, Neil Walker, Zimmern R, Khoury M. Turning the Pump Handle:  Evolving methods for integrating the evidence on Gene-Disease Association. Am J Epidemiol 2007; 166 (8): 863–866

2006

Wood A, White I, Danesh J, Thompson S. Assessing long-term variability in plasma fibrinogen among 27247 adults in 15 prospective studies: an individual participant meta-analysis.  Int’l Jnl Epidemiology 2006; 35: 1570–1578

Ye Z, Liu EH, Higgins JPT, Keavney BD, Lowe GDO, Collins R, Danesh J. Seven haemostatic gene polymorphisms in coronary disease: meta-anaysis of 66155 cases and 91307 controls.  Lancet 2006: 367: 651–658

Ye Z, Song H, Higgins JPT, Pharoah P, Danesh J. Five glutathione S-transferase Gene variants in 23452 cases of lung cancer and 30397 controls: meta-analysis of 130 studies.  PLoS Medicine 2006; 35: 935–943

Thompson A, Danesh J. Associations between apolipoprotein B, apolipoprotein AI, the apoliprotein B/AI ration and coronary heart disease: a literature-based meta-analysis of prospective studies.  J Int Med 2006; 259 (5): 481–492

Keavney B, Danesh J, Parish S, Palmer A, Clark S, Youngman L, Delepine M, Lathrop M, Peto R, Collins R. Fibrinogen and coronary heart disease: test of causality by Mendelian randomization.  Int J Epidemiol 2006; 35: 935–943

Sattar N, Wannamethee G, Sarwar N, Tchernova J, Cherry L, Wallace M, Danesh J, Whincup PH. Adiponectin and Coronary Heart Disease: A Prospective Study and Meta-Analysis. Circulation 2006:  114; 623–629

2003-5

Danesh J, Wheeler J, Hirschfield G, Eda S, Eiriksdottir G, Rumley A, Lowe G, Pepys M, Gudnason V. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Eng J Med 2004;350: 1387–97.

Fibrinogen Study Collaboration (writing committee Danesh J, Lewington S, Thompson S, Lowe GDO, Collins R). Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality. An individual participant meta-analysis. JAMA 2005; 294:1799–1809

Khaw KT, Reeve J, Luben R, Bingham S, Welch A, Wareham N, Oakes S, Day N. Quantitative ultrasonometry of the calcaneus predicts total and hip fractures in men and women: the EPIC-Norfolk prospective population study. Lancet 2004; 363:197–202

Norat T, Bingham S, Ferrari P, Slimani N, Jenab, M, Mazuir M, Overvad K, Olsen A, Tjonneland A, Clavel F, Boutron-Ruault M-C, Kesse E, Boeing H, Bergmann MM, Nieters A, Linseisen J, Trichopoulou D, Tountas Y, Berrino F, Palli D, Panico S, Tumino R, Vineis P, Bueno-de-Mesquita HB, Peeters PHM, Engeset D, Lund E, Skeie G, Ardanaz E, Gonzalez C, Navarro C, Quiros JR, Sanchez M-J, Berglund G, Mattisson I, Hallmans G, Palmqvist R, Day NE, Khaw K-T, Key TJ, Joaquin MS, Hemon B, Saracci R, Kaaks R, Riboli E. Meat, Fish, and Colorectal Cancer Risk: The European Prospective Investigation into Cancer and Nutrition. J Natl Cancer Inst 2005; 97(12): 906–16

The CHEK2 Breast Cancer Case-Control Consortium. CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065controls from ten studies. Am J Hum Genet 2004; 74:1175–1182

Thompson D, Duedal S, Kirner J, McGuffog L, Last J, Reiman A, Byrd P, Taylor M, Easton D. Cancer risks and mortality in heterozygous ATM mutation carriers. J Natl Cancer Inst 2005 97:813–22

Ferri CP, Brayne C, Brodaty H, Fratiglioni L, Ganguli M, Hall K, Hasegawa K, Hendrie H, Huang Y, Jorm A, Mathers C, Menezes P, Prince M, Rimmer E, Scazufca M. One hundred years on – the global prevalence of Alzheimer’s disease and other dementias. The Lancet 2005; 366: 2112 – 2117, 17 December 2005. (abstract)

Khaw KT, Wareham N, Bingham S, Luben R, Welch A, Day N. Association of glycated hemoglobin with cardiovascular disease and mortality in adults: the EPIC-Norfolk prospective study. Ann Int Med 2004;141:413–20.

Sandhu MS, Heude B, Young EH, Luben R, Luan J, Khaw, KT, Todd JA, Wareham NJ. INS VNTR Class Genotype and Indexes of Body Size and Obesity: Population-Based Studies of 7,999 Middle-Aged Men and Women. Diabetes. 2005 ;54(9):2812–2815

Didkowska J, Manczuk M, McNeill A, Powles J, Zatonski W. Lung cancer mortality at ages 35–54 in the European Union: ecological study of evolving tobacco epidemics. BMJ 2005; 331 (7510) : 189–91.