Tel: 01223 746857
Dr Babb de Villiers completed her undergraduate studies at the University of Liverpool (BSc) and Glasgow University (MSc Medical Genetics). She then did a PhD at Stellenbosch University, South Africa where she investigated candidate genes for association with tuberculosis in the South African Cape Coloured population. This is a unique population with a diverse genetic background that allowed her to gain experience in working on complex genetic profiles. She joined the Somatic Cell Genetics Unit’s research and development group in the Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg. She worked on developing diagnostic tests and researched the molecular profile of HIV associated lymphomas, gastrointestinal stromal tumours (GIST) and colorectal cancers. She then transferred to the South African National Cancer Registry, where she was the lead Medical Scientist on the Johannesburg Cancer Study (JCS). She gained experience in cancer epidemiology, cancer registries and was awarded a Union for International Cancer Control International Cancer Technology Transfer Fellowship to the Cancer Council NSW, Sydney (Australia).
She is now working as a Research Associate on the Canrisk project. The overall aim of the Cancer Research UK-funded CanRisk programme is to develop and validate new approaches for breast and ovarian cancer risk stratification and prevention that take advantage of discoveries in both cancer genomics and epidemiology. This includes the development of user-friendly cancer risk assessment tools as the ‘front-ends’ for the cancer risk prediction models for use in healthcare. The CanRisk tool evaluation study aims to understand the usefulness and usability of this front-end tool by healthcare practitioners in a consultation.
Chen WC, Kerr R, May A, Ndlovu B, Sobalisa A, Duze ST, Joseph L, Mathew CG, Babb de Villiers CL The integrity and yield of genomic DNA isolated from whole blood following long-term storage at -30 degree Celsius. Biopreservation and Biobanking 2018 in press
Carver T, Cunningham AP, Babb de Villiers C, Lee A, Hartley S, Tischkowitz M, Walter FM, Easton DF, Antoniou AC. pedigreejs: a web-based graphical pedigree editor. Bioinformatics 2017 Oct 31.
Schonfeld SJ, Erdmann F, Wiggill F, Singh E, Kellett P, Babb C and Schüz J. Hematologic malignancies in South Africa 2000-2006: Analysis of data reported to the National Cancer Registry. Cancer Medicine 2016
Halec G, Schmitt M, Egger S, Abnet CC, Babb C, Dawsey SM, Flechtenmacher C, Gheit T, Hale M, Holzinger D, Malekzadeh R, Taylor PR, Tommasino M, Urban MI, Waterboer T, Pawlita M, Sitas F; InterSCOPE Collaboration. Mucosal Alpha-Papillomaviruses are not associated with Esophageal Squamous Cell Carcinomas: Lack of Mechanistic Evidence from South Africa, China and Iran and from a World-Wide Meta-Analysis. Int J Cancer. 2015 Nov 3.
Singh E, Ruff P, Babb C, Sengayi M, Beery M, Khoali L, Kellett P, Underwood JM. Establishment of a cancer surveillance programme: the South African experience. Lancet Oncology Volume 16, No. 8, e414–e421, August 2015.
Sengayi M, Babb C, Egger M and Urban MI. HIV testing and burden of HIV infection in black cancer patients in Johannesburg, South Africa: A cross-sectional study. BMC Cancer 2015 15:144
Babb C, Urban M, Kielkowski D, and Kellett P. Prostate Cancer in South Africa: Pathology Based National Cancer Registry Data (1986–2006) and Mortality Rates (1997–2009), Prostate Cancer, Volume 2014 May (2014), Article ID 419801, 9 pages
Baker GL, Babb C, Schnugh DJ, Naylor SJ, Louw M, Goedhals J, Bringuier P, Blay J, Willem P. Molecular characterization of gastrointestinal stromal tumours (GISTs) in a South African population. Oncology Letters 2013 Jan;5(1):155-160.
Boy SC, van Heerden MB, Babb C, van Heerden WF, Willem P. Dominant genetic aberrations and coexistent EBV infection in HIV-related oral plasmablastic lymphomas. Oral Oncol. 2011 Sep;47(9):883-7.
Honorary Associate Researcher at the University of the Witwatersrand, School of Pathology, Faculty of Health Sciences, Division of Human Genetics.
Research Associate at Hughes Hall