Professor / Director of Research
Tel: +44 (0) 1223 748652
Professor Simon Thompson is Director of Research in Biostatistics in the Cardiovascular Epidemiology Unit within the Department of Public Health and Primary Care. He is a Fellow of the Academy of Medical Sciences, and a Fellow of Wolfson College Cambridge. From 2000-2011 he was Director of the MRC Biostatistics Unit in Cambridge, an internationally acclaimed research institute in medical statistics. He held previous academic appointments at the London School of Hygiene and Tropical Medicine, and as the first Professor of Medical Statistics and Epidemiology at Imperial College London.
His research interests are in meta-analysis and evidence synthesis, clinical trial methodology, health economic evaluation, and cardiovascular epidemiology; he has published widely in these areas. He has collaborated on a number of major clinical trials, recently including all the major UK national trials of screening and treatment for abdominal aortic aneurysms. He has been a strong advocate for biostatistics through his research papers, didactic articles, and contributions to courses and workshops both in the UK and abroad. He has also taken on a number of responsibilities for the MRC, the Royal Statistical Society, and other international professional societies.
Updating in progress
Resche-Rigon M, White IR, Bartlett J, Thompson SG. Multiple imputation for handling systematically missing confounders in meta-analysis of individual participant data. Statistics in Medicine 2013; 32: 4890-4905. [Pubmed ID: 23857554]
Burgess S, Butterworth AS, Thompson SG. Mendelian randomization analysis with multiple genetic variants using summarized data. Genetic Epidemiology 2013; 37: 658-665. [Pubmed ID: 24114802]
Independent UK Panel on Breast Cancer Screening (Marmot MG, Altman DG, Cameron DA, Dewar JA, Thompson SG, Wilcox M). The benefits and harms of breast cancer screening: an independent review. British Journal of Cancer 2013; 108: 2205-2240. [Pubmed ID:23744281]
Sanderson J, Thompson SG, White IR, Aspelund T, Pennells L. Derivation and assessment of risk prediction models using case-cohort data. BMC Medical Research Methodology 2013; 13: 113. [Pubmed ID: 24034146]
Thompson SG, Brown LC, Sweeting MJ, Bown MJ, Kim LG, Glover MJ, Buxton MJ, Powell JT; the RESCAN Collaborators. Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness. Health Technology Assessment 2013; 17: v-118. [Pubmed ID:24067626]
Burgess S, Thompson SG. Use of allele scores as instrumental variables for Mendelian randomization. International Journal of Epidemiology 2013; 42: 1134-1144. [Pubmed ID: 24062299]
Wormser D, White IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration. Within-person variability in calculated risk factors: comparing the aetiological association of adiposity ratios with risk of coronary heart disease. International Journal of Epidemiology 2013; 42: 849-859. [PMID:23918853]
Lunn DJ, Barrett J, Sweeting MJ, Thompson SG. Fully Bayesian hierarchical modelling in two stages, with application to meta-analysis. Journal of the Royal Statistical Society (Series C, Applied Statistics) 2013; 62: 551-572. [PMID: 24223435]
Powell JT, Thompson SG. Editorial: “Should the frequency of surveillance for small abdominal aortic aneurysms be reduced?”. European Journal of Vascular and Endovascular Surgery 2013; 46: 171-172. [Pubmed ID: 23689180]
RESCAN Collaborators (Bown MJ, Sweeting MJ, Brown LC, Powell JT, Thompson SG). Surveillance intervals for small abdominal aortic aneurysms: an individual patient data meta-analysis. Journal of the American Medical Association 2013; 309: 806-813. [Pubmed ID: 23443444]