Research Group Leader
Telephone: +44 01223 761930
I have 25 years experience as a laboratory scientist in the genetic epidemiology of common diseases – formerly studying cardiovascular disease and more recently cancer. My principle role, within our team is to link the science of genetic epidemiologic with the technological capabilities of the High-throughput Laboratory located here in the SRL. Currently the main research themes within the laboratory are post Genome-wide Association Studies (GWAS) confirmation and follow-up studies. These include Fine Scale Mapping projects, which aim to identify the directly causative variants within genomic loci discovered via GWAS. Skills we learned during our initial Breast Cancer GWAS are now being applied to other traits and diseases – specifically: Susceptibility to Endometrial Cancer, Melanoma and naevus count; Differences in response of normal tissues to Radiotherapy – the RAPPER project; Genetic control of mean telomere length and its effect on cancer susceptibility – the Telomeres project.