In 1991 I joined the Department of Public Health and Primary Care as statistician in a two-year Research Assistant post in the Health and Lifestyle Survey team, following an MSc in Medical Statistics at the University of Southampton. After returning there to undertake a PhD in the area of multilevel modelling applied to child mortality, I joined CAMS as Research Associate in 1996, being the first CAMS consulting statistician (except for the Director!).
In 2000 I moved to a joint post between CAMS and the General Practice and Primary Care Research Unit as a consulting statistician and as a trial statistician in studies aiming to encourage beneficial changes in physical activity and other lifestyle behaviours to prevent disease.
In 2002 I moved to a Senior Research Associate post in the GP Unit, working in trials and in methodological work in the area of multivariate meta-analysis applied to studies of behaviour change and their psychological determinants, in an attachment with the MRC Biostatistics Unit.
In 2006 I returned to a post in CAMS, being more involved in design-stage consulting and contributing to research protocols. I am part-funded by the GP Unit as senior statistician working predominantly in Type 2 Diabetes trials and with research collaborators at Kings College London. I am linked to University College London as honorary senior lecturer in a collaboration investigating the early detection of cancer.
I continue to have applied and methodological interests in trials and have recently joined with researchers in the Departments of Paediatrics and Oncology in appyling for funding for trials in Type 1 diabetes and Cancer.
Collaborations leading to publication
Methods
- Prevost AT, Mason D, Griffin S, Kinmonth AL, Sutton S, Spiegelhalter D
Allowing for correlations between correlations when carrying out random-effects meta-analysis of correlation matrices.
Code available for download - Fanshawe T, Prevost AT, Roberts JS, Green RC, Armstrong D, Marteau T (Submitted).
Assessing the behavioural impact of predictive DNA testing: the problem of collinearity between type of test and risk estimates generated from them. - Mason D, Prevost AT, Sutton S (Accepted).
Perceptions of absolute versus relative differences between personal and comparison health risk. - Turner RM, Prevost AT, Thompson SG (2004).
Allowing for imprecision of the intracluster correlation coefficient in the design of cluster randomized trials.
Statistics in Medicine, 23, 1195-1214.
Bister D, Edler RJ, Tom BDM, Prevost AT (2002).
Natural head posture – considerations of reproducibility.
European Journal of Orthodontics, 24, 457-470.
McDonald JW, Prevost AT (1997).
The fitting of parameter-constrained demographic models.
Mathematical and Computer Modelling, 26, 79-88.
Prevost AT (1996).
Multilevel modelling of child mortality: Gibbs sampling versus other approaches.
PhD thesis under McDonald JW, University of Southampton.
Trials
Kellar I, Prevost AT, Griffin S, Sutton S, Kinmonth AL, Marteau T (Submitted).
A randomized trial to develop an informed choice invitation to Type 2 diabetes screening.
Emery J, Morris H, Goodchild R, Fanshawe T, Prevost AT, Bobrow M, Kinmonth AL (2007).
The GRAIDS Trial: a cluster randomised controlled trial of computer decision support for the management of familial cancer risk in primary care. British Journal of Cancer, 97, 486-493
D’Vaz AP, Ostor AJK, Speed CA, Jenner JR, Bradley M, Prevost AT, Hazleman BL (2006).
Pulsed low-intensity ultrasound therapy for chronic lateral epicondylitis: a randomized controlled trial. Rheumatology, 45, 566-570.
Williams K, Prevost AT, Griffin S, Hardeman W, Hollingworth W, Spiegelhalter D, Sutton S, Ekelund U, Wareham N, Kinmonth AL (2004).
The ProActive trial protocol – a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766].
BMC Public Health, 4, 48-59.
Available to read
Brown PJB, Warmington V, Laurence M, Prevost AT (2003).
Randomised crossover trial comparing the performance of Clinical Terms Version 3 and Read Codes 5 byte set coding schemes in general practice.
British Medical Journal, 326, 1127-1130.
Available to read
Hunt PJ, Gurnell EM, Huppert FA, Richards C, Prevost AT, Wass JAH, Herbert J, Chatterjee VKK (2000).
Improvement in mood and fatigue after dehydroepiandrosterone Replacement in Addison’s Disease in a randomized, double blind trial.
Journal of Clinical Endocrinology and Metabolism, 85, 4650-4656.
Burch S, Longbottom J, McKay M, Borland C, Prevost T (2000).
The Huntingdon Day Hospital Trial: Secondary outcome measures.
Clinical Rehabilitation, 14, 447-453.
Burch S, Longbottom J, McKay M, Borland C, Prevost T (1999).
A randomised controlled trial of day hospital and day centre therapy.
Clinical Rehabilitation, 13, 105-112.
Robinson SM, Mackenzie-Ross S, Campbell-Hewson GL, Egleston CV, Prevost AT (1998).
Psychological effect of witnessed resuscitation on bereaved relatives.
The Lancet, 352, 614-617.
Hughes VF, Trull AK, Gimson A, Friend PJ, Jamieson N, Duncan A, Wight DGD, Prevost AT, Alexander GJM (1997).
Randomized trial to evaluate the clinical benefits of serum a-glutathione S-transferase concentration monitoring after liver transplant.
Transplantation, 64, 1446-1452.
Meta-analysis
Naughton F, Prevost AT, Sutton S (Submitted).
Self-help smoking cessation interventions in pregnancy – a systematic review and meta-analysis.
Baguley DM, Bird J, Humphriss RL, Prevost AT (2006).
The evidence base for the application of contralateral bone anchored hearing aids in acquired unilateral sensorineural hearing loss in adults.
Clinical Otolaryngology, 31, 6-14.
Braithwaite D, Emery J, Walter F, Prevost AT, Sutton S (2004).
Psychological impact of genetic counseling for familial cancer: a systematic review and meta-analysis.
Journal of the National Cancer Institute, 96, 122-133.
Available to read
Primary care
Ostor AJK, Richards CA, Prevost AT, Speed CA, Hazleman BL (2005).
Diagnosis and relation to general health of shoulder disorders presenting to primary care.
Rheumatology, 44, 800-805.
Brown PJB, Warmington V, Laurence M, Prevost AT (2003).
A methodology for the functional comparison of coding schemes in primary care.
Informatics in Primary Care, 11, 145-148.
Whitford DL, Griffin SJ, Prevost AT (2003).
Influences on the Variation in Prevalence of Type 2 Diabetes between General Practices: practice, patient or socioeconomic factors?
British Journal of General Practice, 53, 9-14.
Bird JC, Beynon GJ, Prevost AT, Baguley DM (1998).
An analysis of referral patterns for dizziness in the primary care setting.
British Journal of General Practice, 48, 1828-1832.
Cancer detection
Shetty A, Loddo M, Fanshawe T, Prevost AT, Sainsbury R, Williams GH, Stoeber K (2005).
DNA replication licensing and cell cycle kinetics of normal and neoplastic breast.
British Journal of Cancer, 93, 1295-1300.
Kingsbury SR, Loddo M, Fanshawe T, Obermann EC, Prevost AT, Stoeber K, Williams GH (2005).
Repression of DNA replication in quiescence is independent of geminin and may define the cell cycle state of progenitor cells.
Experimental Cell Research, 309, 56-67.
Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH (2004).
DNA replication licensing in somatic and germ cells.
Journal of Cell Science, 117, 5875-5896.
Williams GH, Swinn R, Prevost AT, de Clive-Lowe P, Halsall I, Going JJ, Hales CN, Stoeber K, Middleton SJ (2004).
Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates.
British Journal of Cancer, 91, 714-719.
Stoeber K, Swinn R, Prevost AT, de Clive-Lowe P, Halsall I, Dilworth SM, Marr J, Turner WH, Bullock N, Doble A, Hales CN, Williams GH (2002).
Diagnosis of Genito-Urinary Tract Cancer by Detection of Minichromosome Maintenance 5 Protein in Urine Sediments.
Journal of the National Cancer Institute, 94, 1071-1079.
Available to read
Secondary care
Cross JJ, Baguley DM, Antoun NM, Moffat DA, Prevost AT (2006).
Reproducibility of volume measurements of Vestibular Schwannomas – a preliminary study.
Clinical Otolaryngology, 31, 123-129.
Koo BC, Ng CS, U-King-Im J, Prevost AT, Freeman AH (2006).
Minimal preparation CT for the diagnosis of suspected colorectal cancer in the frail and elderly patient.
Clinical Radiology, 61, 127-139.
Ng CS, Doyle TC, Pinto EM, Courtney HM, Bull RK, Prevost AT, Campbell GA, Freeman AH, Dixon AK (2002).
Evaluation of CT in identifying colorectal carcinoma in the frail and disabled patient.
European Journal of Radiology, 12, 2988-2997.
Burnet NG, Routsis DS, Murrell P, Burton KE, Taylor PJ, Thomas SJ, Williams MV, Prevost AT (2001).
A tool to measure radiotherapy complexity and workload: Derivation from the Basic Treatment Equivalent (BTE) concept.
Clinical Oncology, 13, 14-23.
Ostor AJK, Richards CA, Prevost AT, Hazleman BL, Speed CA (2004).
Interrater reproducibility of clinical tests for rotator cuff lesions.
Annals of the Rheumatic Diseases, 63, 1288-1292.
Iles R, Legh-Smith J, Drummond M, Prevost AT, Vowler S on behalf of the Pharmacoeconomics Study Group (2003).
Economic evaluation of Tobramycin nebuliser solution in cystic fibrosis.
Journal of Cystic Fibrosis, 2, 120-128.
Sparkes V, Prevost AT, Hunter JO (2003).
Derivation and identification of questions that act as predictors of abdominal pain of musculoskeletal origin.
European Journal of Gastroenerology and Hepatology, 15, 1021-1027.
Parker TJ, Woolner JT, Prevost AT, Tuffnell Q, Shorthouse M, Hunter JO (2001).
Irritable bowel syndrome: is the search for lactose intolerance justified?
European Journal of Gastroenterology and Hepatology, 13, 219-225.
Gelling L, Prevost AT (1999).
The needs of relatives of critically ill patients admitted to a neurosciences critical care unit: A comparison of the perceptions of relatives, nurses and doctors.
Care of the Critically Ill, 15, 53-58.
Complex interventions and lifestyle behaviours
Hardeman W, Michie S, Fanshawe T, Prevost AT, McLoughlin K, Kinmonth AL (Accepted).
Fidelity of delivery of a physical activity intervention: Predictors and consequences.
Michie S, Hardeman W, Fanshawe T, Prevost AT, Taylor L, Kinmonth AL (Accepted).
What is a theory-based intervention? The case study of ProActive.
Williams DEM, Prevost AT, Whichelow MJ, Cox BD, Day NE, Wareham NJ (2000).
A cross-sectional study of dietary patterns with Glucose Intolerance and other features of the metabolic syndrome.
British Journal of Nutrition, 83, 257-266.
Cox BD, Whichelow MJ, Prevost AT (2000).
Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer.
Public Health Nutrition, 78, 873-888.
Prevost AT, Whichelow MJ, Cox BD (1997).
Longitudinal dietary changes between 1984-5 and 1991-2 in British adults: associations with socio-demographic, lifestyle and health factors.
British Journal of Nutrition, 78, 873-888.
Whichelow MJ, Prevost AT (1996).
Dietary patterns and their association with demographic, lifestyle and health parameters in a random sample of British adults.
British Journal of Nutrition, 76, 17-30.
Cox BD, Whichelow MJ, Prevost AT (1998).
The development of cardiovascular disease in relation to anthropometric indices and hypertension in British adults.
International Journal of Obesity, 22, 966-973.
Cox BD, Prevost AT, Whichelow MJ (1997).
Associations of smoking with prescribed medications, arthritis/rheumatism and back problems in the British Health and Lifestyle Survey follow-up respondents.
European Journal of Public Health, 7, 311-317.
Blaxter M, Prevost AT (1993).
Patterns of mortality. In The Health & Lifestyle Survey: 7 Years On, Cox BD, Huppert, FA & Whichelow MJ (eds)
Dartmouth Publishing Co. Ltd., 33-46.
Available abstracts